The causal involvement of the BDNF-TrkB pathway in dentate gyrus in early-life stress-induced cognitive deficits in male mice.

Transl Psychiatry · 2023 · PMC10209152 · PMID 37225683

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0.0670

closest p · 1.3× alpha

0.0670

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The sentences

showed a trendp = 0.067so close (0.05 < p ≤ 0.1)

1B ), unlike control mice ( t 12 = 9.957, p < 0.0001, n = 13, one-sample t test), mice in the ELS group only showed a trend to discriminate the displaced object from the non-displaced one ( t 10 = 2.053, p = 0.067, n = 11, one-sample t test) and exhibited significantly lower preference index than the CT group ( t 22 = 2.522, p = 0.019; unpaired t test), indicating that ELS induces spatial memory deficits.

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