This was in line with an enrichment of variants with nominally significant allele frequency difference between the two studies (37 of 534 PGS_eGFRcrea variants and 17 of 186 PGS_eGFRcys variants with p diff < 0.05; binomial enrichment for success probability ≥ 0.05 under the null: p bin = 0.030 or 0.013, respectively).
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Polygenic scores for estimated glomerular filtration rate in a population of general adults and elderly - comparative results from the KORA and AugUR study.
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