Critical Illness-Related Corticosteroid Insufficiency (CIRCI) Among Patients with COVID-19 at a Tertiary Hospital: Clinical Characteristics and Outcomes.

However, other trials on patients afflicted with influenza A/H1N1 failed to detect any improvement in symptoms and even showed a trend towards an increase in mortality rate with glucocorticoid use. 13 In these trials though, patients in the glucocorticoid arm had a more severe illness which could possibly account for the increase in mortality rate observed in these cohorts. 15 For patients with SARS pneumonia, data from Guangzhou showed that 79.6% of patients who were given glucocorticoids had a lower mortality rate and shorter duration of hospitalization.

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