Supplement Treatment with NAC and Omega-3 Polyunsaturated Fatty Acids during Pregnancy Partially Prevents Schizophrenia-Related Outcomes in the Poly I:C Rat Model.

A significant difference in reversal learning was found across groups (day 2, H (5) = 13.506, p = 0.019), as the adult offspring of Poly I:C rats showed a trend towards rapid reversal (post hoc p = 0.051), indicative of excessive switching behavior, which was significantly improved following prenatal exposure to omega-3 PUFAs (post hoc p = 0.045) ( Figure 4 B and Table S2 in Supplementary Materials ).

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