The Acute Radiation Syndrome-Mitigator Romiplostim and Secreted Extracellular Vesicles Improved Survival in Mice Acutely Exposed to Myelosuppressive Doses of Ionizing Radiation.

In mice with severe ARS treated with 0 Gy + NSS EVs ( Figure 2 A), 0 Gy + RP EVs ( Figure 2 B), and TBI + NSS EVs ( Figure 2 C), the 30-day survival rate improved to 25%; however, the difference did not reach statistical significance ( p = 0.072, p = 0.22, and p = 0.069, respectively).

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