Overall, MYC showed a trend of increased frequency of positive expression in recurrent/metastatic FN RMS, and YBX1 was expressed in all primary and metastatic FN and FP RMS tumor tissue samples examined ( Figure 7 B), suggesting that MYC and YBX1 play a role in both primary and recurrent/metastatic RMS tumors.
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The MYC-YBX1 Circuit in Maintaining Stem-like Vincristine-Resistant Cells in Rhabdomyosarcoma.
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