Lipocalin-2 Deficiency Diminishes Canonical NLRP3 Inflammasome Formation and IL-1β Production in the Subacute Phase of Spinal Cord Injury.

Int J Mol Sci · 2023 · PMC10218144 · PMID 37240031

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did not reach statistical significanceno p-value reported

Interestingly, Lcn2 −/− mice showed a decreased GFAP + NLRP3 + ( p = 0.1089, df = 2, F = 10.72) and GFAP + PYCARD + ( p = 0.1482, df = 2, F = 8.213) population in the lesion site at 7 days post-SCI compared with WT mice, which did not reach statistical significance ( Figure 6 ). 3.

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