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TREM2 Expression and Amyloid-Beta Phagocytosis in Alzheimer's Disease.

Int J Mol Sci · 2023 · PMC10218378 · PMID 37239970

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TREM2 mRNA in Monocytes of AD and HC A two-fold increase in TREM2 mRNA expression was observed in unstimulated (medium) monocytes of AD (median = 2488 copies/ng) compared to HC (median = 1230 copies/ng) ( Figure 2 ); this difference approached but did not reach statistical significance.

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