nearly significantp = 0.07
For G/G and G/A, there was a nearly significant trend toward less aggressive disease over time with a mean reduction of −1.3 + −9.2 (95%CI −3.4 to 0.2) ( p = 0.07) of the SELENA-SLEDAI; for A/A, there was a non-significant increase of + 2.7 + −4.1 (95%CI 7.7 to 13.0) ( p = 0.38).