Gut microbiota, circulating inflammatory markers and metabolites, and carotid artery atherosclerosis in HIV infection.

Microbiome · 2023 · PMC10224225 · PMID 37237391

Europe PMC DOI

hedged sentences

0.0640

closest p · 1.3× alpha

0.0640

boldest claim

The sentences

marginally significantP = 0.064so close (0.05 < p ≤ 0.1)

ignava showed a marginally significant association with carotid artery plaque ( P = 0.064), and the association was abolished after further adjustment for conventional CVD risk factors ( P = 0.212).

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showed a trendno p-value reported

In addition, we also found another microbiota-related metabolite, 3-hydroxyhippuric acid, which showed a trend of positive association with carotid artery plaque and also positive associations with several inflammatory markers. 3-hydroxyhippuric acid is a microbial aromatic acid metabolite derived from dietary polyphenols and flavonoids [ 66 ] through microbial metabolism [ 49 ].

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