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A Case of Mixed Connective Tissue Disease That Transformed Into Systemic Lupus Erythematosus After a Long Clinical Course.

Cureus · 2023 · PMC10224699 · PMID 37252562

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showed a trendno p-value reported
The anti-SM and anti-RNP antibody dual-positive cases showed a trend toward early onset, with an average age of 0.59 years.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.