Genome-wide DNA methylation profiling of HPV-negative leukoplakia and gingivobuccal complex cancers.

Clin Epigenetics · 2023 · PMC10225107 · PMID 37245006

Europe PMC DOI

hedged sentence

0.0100

closest p · 0.2× alpha

0.0100

boldest claim

The sentences

nominally significantP = 0.010actually significant

A gain in ISG15 was nominally significantly associated with better recurrence-free survival (RFS) [HR (95% CI):0.40 (0.2–0.80), P = 0.010], disease-specific survival (DSS) [HR:0.30 (0.13–0.71), P = 0.006] and overall survival (OS) [HR:0.31 (0.14–0.69), P = 0.004], but not after correction for multiple testing.

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