Pharmacogenomic-guided dosing of fluoropyrimidines beyond <i>DPYD</i>: time for a polygenic algorithm?

Front Pharmacol · 2023 · PMC10226670 · PMID 37256234

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closest p · 0.7× alpha

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boldest claim

The sentences

showed a trendp = 0.035actually significant

Rs2241409 showed a trend towards association with grade ≥3 HFS ( p = 0.035), however, this association is not statistically significant at the threshold set in the study ( Rosmarin et al., 2014 ).

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