The Effectiveness of Eplerenone vs Spironolactone on Left Ventricular Systolic Function, Hospitalization and Cardiovascular Death in Patients With Chronic Heart Failure-HFrEF.

Med Arch · 2023 · PMC10227849 · PMID 37260796

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did not reach statistical significanceno p-value reported

( 13 , 19 - 22 ) Our findings are consistent with most of these studies, as measures of left ventricular end-diastolic volume, left ventricular end-systolic volume, and LV ejection fraction tend to improve in both arms but more with eplerenone, although the reductions in end-diastolic volume did not reach statistical significance.

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