Functional ultrasound detects frequency-specific acute and delayed S-ketamine effects in the healthy mouse brain.

The only frequency bands where changes were present was slow1-2, including decreases between BLA and Peri ( p < 0.01) at edge level and reductions ( p < 0.05) in global ( Z = −2.1), ACg ( Z = −2.2), S1 ( Z = −2.2), Au ( Z = −2.0), TAs ( Z = −2.1), and CPu ( Z = −2.2) FC strengths, while decreases approaching significance levels were observed in a number of other regions.

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