Although there was no significance in Caspase3 activation in MKN45 cells, there was a clear trend of upregulated cleaved-Caspase3 expression ( Figure 4E ).
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The sentences
Serum levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) showed an increasing trend after treatment with 50 mg/kg acacetin, but the absolute value did not exceed 1 ng/mL ( Supplementary Figure S7 ).