ANOVA revealed main effects on the alternation score of kainate treatment [sham-control versus epileptic: F (1,44) = 7.36, P = 0.0095], but the effects of ICA-121431 treatment did not reach statistical significance [ F (1,44) = 2.86, P = 0.098; interaction: F (1,44) = 0.82, P = 0.59; Fig. 7M , Bonferroni’s post-tests indicated with asterisks].
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Targeting aberrant dendritic integration to treat cognitive comorbidities of epilepsy.
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