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C4b-binding protein inhibits particulate- and crystalline-induced NLRP3 inflammasome activation.

Front Immunol · 2023 · PMC10239802 · PMID 37283747

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When we analysed IL-18 secretion we found that there was tendency, which did not reach statistical significance, towards recombinant C4BP inhibition of MSU- and SiO 2 -induced IL-18 secretion ( Figure 4B ).

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