Regarding the latter, the increasing use of older donors and the more likely presence of gene mutations associated with clonal hematopoiesis of indeterminate significance (CHIP) in older populations is an emerging concern ( Nawas et al. 2021 ).
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Clonal cytopenia of undetermined significance (CCUS)-associated reversion of donor-derived, transient αβ T-cell large granular clonal lymphocytosis, emerging post-transplant in a patient with a history of γδ T-cell large granular lymphocytic leukemia.
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