In addition, there has been a strong trend toward the procedure being performed in older patients with less favorable anatomy and greater comorbidities with attendant less favorable results and substantially higher complication rates 53 , 54 ; this may reflect waning of experience by operators as well as the greater inherent risk in these patients.
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The 40th Anniversary of Percutaneous Balloon Valvuloplasty for Mitral Stenosis: Current Status.
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The severity of PHT and signs of right heart failure are highly significant; PHT is frequently reversible in young patients with severe MS, but this is less predictable in older patients where the pulmonary circulation is more likely to have undergone irreversible changes.