Barely Significant
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The 40th Anniversary of Percutaneous Balloon Valvuloplasty for Mitral Stenosis: Current Status.

Struct Heart · 2022 · PMC10242581 · PMID 37288059

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a strong trendno p-value reported
In addition, there has been a strong trend toward the procedure being performed in older patients with less favorable anatomy and greater comorbidities with attendant less favorable results and substantially higher complication rates 53 , 54 ; this may reflect waning of experience by operators as well as the greater inherent risk in these patients.

also in 5,725 other papers

highly significantno p-value reported
The severity of PHT and signs of right heart failure are highly significant; PHT is frequently reversible in young patients with severe MS, but this is less predictable in older patients where the pulmonary circulation is more likely to have undergone irreversible changes.

also in 132,142 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.