A high-throughput test enables specific detection of hepatocellular carcinoma.

Nat Commun · 2023 · PMC10247794 · PMID 37286539

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nominally significantno p-value reported

All 5 CpG positions included in “HCC-detect” and “HCC-spec” are significantly more methylated than in either healthy controls, chronic hepatitis B or both or non-HCC cancers ( CCNJ is nominally significant when compared to healthy controls and significant against chronic hepatitis B).

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somewhat significantno p-value reported

However, there was a somewhat significant lower alcohol use and higher fraction of smokers in the HCC groups (Table 2 ).

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