Short-Term Irisin Treatment Enhanced Neurotrophin Expression Differently in the Hippocampus and the Prefrontal Cortex of Young Mice.

Int J Mol Sci · 2023 · PMC10252658 · PMID 37298063

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hedged sentences

0.0590

closest p · 1.2× alpha

0.0810

boldest claim

The sentences

near to significancep = 0.059so close (0.05 < p ≤ 0.1)

Indeed, we noticed a considerable increase in BDNF mRNA levels ( p < 0.0001) and a value near to significance for Fgf-2 ( p = 0.059) in irisin-treated mice compared to controls.

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did not reach statistical significancep = 0.081so close (0.05 < p ≤ 0.1)

In the PFC, we found a slight increase in Il-6 expression in irisin-treated mice that nonetheless did not reach statistical significance ( p = 0.081), while no differences were noticed for Il-1β ( p = 0.409) ( Figure 4 ).

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