A Novel Time-Resolved Fluorescence Resonance Energy Transfer Assay for the Discovery of Small-Molecule Inhibitors of HIV-1 Tat-Regulated Transcription.

Int J Mol Sci · 2023 · PMC10252837 · PMID 37298089

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showed a trendno p-value reported

The IC 50 values of these inhibitors obtained in our assay showed a trend similar to those of the previously described dissociation constants (K d ) and IC 50 values determined by their distinctive assays [ 35 , 36 ] ( Figure 3 C).

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