Functional IgG Autoantibodies against Autonomic Nervous System Receptors in Symptomatic Women with Silicone Breast Implants.

Validity of the open field analysis was further supported by conducting the behavioral paradigm four days after the injection (Day 5), while a complete disappearance of the SBI-IgG effect was observed along with no significant effect on the animals’ preference for the center, though a slight trend was still identifiable ( Figure 3 G–L).

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This effect was accompanied with a strong trend of reduction of the locomotor activity of the SBI-IgG treated mice, indicating an overall apathic-like behavior.

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