For in vitro preparations of pig retina, activation remained high for at least 24 h [ 8 ]; in vivo, RhoA-GTP levels are higher 24 h after detachment compared to the control retina, but this increase did not reach statistical significance (n = 4 animals, t -test, p = 0.07, unpublished data).
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Injury to Cone Synapses by Retinal Detachment: Differences from Rod Synapses and Protection by ROCK Inhibition.
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