Neural dysregulation in post-COVID fatigue.

The StartReact effect, which measures the acceleration of a visual reaction time by a loud (startling) sound and has been proposed to assess reticulospinal pathways, 36 showed a trend to increase in the biceps muscle in pCF subjects ( STR_Bic , 38.7 ± 34.1 versus 25.1 ± 12.3 ms, P = 0.010) but did not survive correction for multiple comparisons and was not significantly different in the first dorsal interosseous ( STR_1DI ).

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For the metrics that failed to reach significance individually, it was important to determine if they could still distinguish between pCF and controls in combination.

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