Gut microbiota and type 1 diabetes: a two-sample bidirectional Mendelian randomization study.

Significant results were those with the P FDR < 0.1; meanwhile P < 0.05 but P FDR > 0.1 was considered as nominally significant. 3 Results 3.1 Causal association of four dominant phyla and their subcategories with T1D At the phylum level, 15 index SNPs were selected to genetically predict Actinobacteria, 10 index SNPs were selected to genetically predict Bacteroidetes, 14 index SNPs were selected to genetically predict Firmicutes, and 12 index SNPs were selected to genetically predict Proteobacteria.

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