Microsurgical Breast Reconstruction in Patients with Disorders of Hemostasis: Perioperative Risks and Management.

One earlier study had shown that multidisciplinary care and management involving a hematologist in hypercoagulable patients had a positive correlation with improved flap outcomes, although this did not reach statistical significance ( p = 0.064). 19 Many study groups limit thrombophilia screening to factor V Leiden mutation; prothrombin mutation G20210A; the inhibitors antithrombin, protein C, and protein S; and possibly to the autoantibodies to detect antiphospholipid syndrome.

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