Early metabolic alterations in the normal‑appearing grey and white matter of patients with clinically isolated syndrome suggestive of multiple sclerosis: A proton MR spectroscopic study.

Exp Ther Med · 2023 · PMC10265702 · PMID 37324507

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did not reach statistical significanceno p-value reported

Additionally, the concentration of Glth was increased in the CIS group compared with that in HCs in both applied voxels, but the difference did not reach statistical significance.

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a trend toward significanceno p-value reported

In the CIS-treated-group tNAA(cs) was significantly higher and tCr(cs) was also elevated showing a trend toward significance ( Table III , Fig. 3A ).

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