Long non-coding RNA lncMGC mediates the expression of TGF-β-induced genes in renal cells via nucleosome remodelers.

lncMGC-KO5 MMC, which showed a trend toward lower miR-379 expression than KO1 MMC ( Supplementary Figure S5E ), was used for further studies. 3.3 Transcriptome analysis (RNA-seq) of WT and lncMGC-KO5 MMC reveals TGF-β- and DKD-related functions for lncMGC To test the global transcriptomic effects of lncMGC, RNA-seq was performed on MMC isolated and cultured from WT and lncMGC-KO5 mice ( Figure 2 ).

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