ABCA1 deficiency contributes to podocyte pyroptosis priming via the APE1/IRF1 axis in diabetic kidney disease.

Sci Rep · 2023 · PMC10267156 · PMID 37316538

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0.0800

closest p · 1.6× alpha

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The sentences

did not reach statistical significancep = 0.08so close (0.05 < p ≤ 0.1)

At the protein level, caspase-4 and GSDMD were significantly increased in siABCA1 compared to siCO podocytes (p = 0.007 for pro caspase-4 and 0.0001 for FL-GSDMD), while caspase-1 expression was increased but at a level that did not reach statistical significance (p = 0.08) (Fig. 1 b).

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