CT Radiomics Combined With Clinicopathological Features to Predict Invasive Mucinous Adenocarcinoma in Patients With Lung Adenocarcinoma.

10 Previous studies revealed that the frequency of epidermal growth factor receptor (EGFR) (72.0% vs 40.0% vs 23.1%, P = .002) and ALK (undetected vs 20.0% vs 26.9%, P = .015) alterations showed a trend of gradual decrease and increase from non-IMA to mixed-IMA to pure-IMA, respectively. 11 Another study showed that KRAS mutations were more common in IMA than in other adenocarcinomas (14%-86% in IMA vs 1.5%-17% in non-IMA). 11 – 16 These driver mutations influenced the choice of clinical drug treatment options.

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