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Compromised antigen binding and signaling interfere with bispecific CD19 and CD79a chimeric antigen receptor function.

Blood Adv · 2023 · PMC10275707 · PMID 36469024

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showed a trendno p-value reported
The data showed a trend toward better tumor control with tandem and bicistronic CAR T cells cotargeting CD79a and CD19, as compared with the respective CD79b-CD19 bispecific CAR T cells ( Figure 4 B).

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