A large proportion of patients with a faster decline corresponded to dense deposit disease cases—although the differences did not reach statistical significance—and had been treated with an immunosuppressive regimen different than corticosteroids plus MMF.
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Clinical Profiles and Patterns of Kidney Disease Progression in C3 Glomerulopathy.
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In addition, when kidney survival was analyzed according to the categories of serum C3 levels at the end of follow-up, a nonsignificant trend was observed toward a better survival in patients with C3 levels ≥77 mg/dl ( Supplemental Figure 4 ).