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Humanized APOE genotypes influence lifespan independently of tau aggregation in the P301S mouse model of tauopathy.

Acta Neuropathol Commun · 2023 · PMC10280946 · PMID 37337279

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Cortical AT8 immunoreactivity was somewhat lower in PS/E2H mice compared to PS/E3H and PS/E4H mice, though this did not reach statistical significance due to high variability (Fig. 1 C).

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