Genetic analyses identify brain structures related to cognitive impairment associated with elevated blood pressure.

These IDPs had to additionally demonstrate a nominally significant ( P < 0.05) association with BP when (i) using the weighted median, MR–Egger and robust IVW sensitivity methods, which allowed relaxing certain assumptions, such as lack of genetic pleiotropy, 21 of the MR framework, and (ii) instrumental variables from separate ICBP and UK Biobank cohorts were used in IVW MR analysis.

also in 7,732 other papers