We focused on necroptosis‐related genes in the microarray analysis data and found that necroptosis‐related genes showed a trend of increased expression in the diabetic state compared with the control condition, and decreased expression in the treated (i.e., with linagliptin) condition (Figure 5a–c ).
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Linagliptin ameliorated cardiac fibrosis and restored cardiomyocyte structure in diabetic mice associated with the suppression of necroptosis.
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