The multifaceted nature of IL-10: regulation, role in immunological homeostasis and its relevance to cancer, COVID-19 and post-COVID conditions.

Front Immunol · 2023 · PMC10287165 · PMID 37359549

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Early phase I and II studies showed a trend toward favorable responses of systemically administered IL-10 in psoriasis and Crohn’s disease patients, but larger studies revealed only a slight clinical benefit, due to the double anti- and pro-inflammatory properties of this cytokine ( 43 , 195 ).

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