LAMP2A, and other chaperone-mediated autophagy related proteins, do not decline with age in genetically heterogeneous UM-HET3 mice.

Aging (Albany NY) · 2023 · PMC10292871 · PMID 37315291

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hedged sentences

0.0490

closest p · 1.0× alpha

0.0800

boldest claim

The sentences

marginally significantp = 0.049actually significant

There was a marginally significant effect of age on whole liver LAMP2A levels (p = 0.049 by a main-effects model 2-way ANOVA; the interaction term was not significant in the full model).

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near-significantp = 0.08so close (0.05 < p ≤ 0.1)

We found that fasting significantly reduced the abundance of GAPDH, ACSS2, and FASN (as predicted), and caused a near-significant reduction in IDH1 (p = 0.08) in UM-HET3 liver ( Figure 3 ).

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