Barely Significant
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Impact of perineural invasion on the outcome of patients with synchronous colorectal liver metastases treated with neoadjuvant chemotherapy and surgery.

Clin Transl Oncol · 2023 · PMC10293410 · PMID 37027061

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Second, given the strict selection criteria—the resection of synchronous metastases—the cohort is relatively small which may explain why some parameters did not reach statistical significance.

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