Although the cellular NPs uptake levels showed a trend toward greater expression in PLGA-miR-129+Sp formulation compared with PLGA-miR-129+PEI formulation, there were no significant differences between the two nanoformulations ( P = 0.057, Fig. 5b ).
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Optimization and characterization of miRNA-129-5p-encapsulated poly (lactic-<i>co</i>-glycolic acid) nanoparticles to reprogram activated microglia.
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