Recombinant α₁-Microglobulin (rA1M) Protects against Hematopoietic and Renal Toxicity, Alone and in Combination with Amino Acids, in a ¹⁷⁷Lu-DOTATATE Mouse Radiation Model.

Administration of rA1M, prior to the 177 Lu-DOTATATE administration, had an increasing trend of preserving reticulocyte population with increases in dose compared to the vehicle ( Figure 3 B), although this was not statistically significant.

also in 63,971 other papers

Administration of rA1M showed a clear trend towards reduced proteinuria (i.e., albumin/creatinine ratio) with all concentrations of rA1M, with 2 × 5 mg/kg resulting in a significant reduction ( Figure 3 A).

also in 19,460 other papers