Metabolism of Acetaminophen by Enteric Epithelial Cells Mitigates Hepatocellular Toxicity In Vitro.

J Clin Med · 2023 · PMC10299659 · PMID 37373688

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Intriguingly, Caco-2 cells exposed to APAP showed a trend towards increased tight junction integrity (4 kHz), which was statistically significant at higher (20 mM) APAP concentrations, ( Figure 3 , Endpoint fold change Step 1, 4 kHz).

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