Resveratrol ameliorates the behavioural and molecular changes in rats exposed to uninephrectomy: role of hippocampal SIRT1, BDNF and AChE.

J Physiol Biochem · 2023 · PMC10300160 · PMID 36469209

Europe PMC DOI

hedged sentences

0.0500

closest p · 1.0× alpha

0.0628

boldest claim

The sentences

a significant trendP > 0.05actually significant

Effect of Resveratrol on BDNF, CREB and PPARγ mRNA expression in Unix rats Though both BDNF and CREB mRNA expression was downregulated in Unix rats compared to sham-operated ones, this did not show a significant trend (≥ 0.5-fold, P > 0.05).

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a nonsignificant trendP = 0.0628so close (0.05 < p ≤ 0.1)

Also, Resveratrol tended to decrease the protein/creatinine ratio by about 30% than in untreated Unix rats but with a nonsignificant trend ( P = 0.0628), Table 2 .

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