Inappropriate activation of the renin-angiotensin system improves cardiac tolerance to ischemia/reperfusion injury in rats with late angiotensin II-dependent hypertension.

Front Physiol · 2023 · PMC10301744 · PMID 37389123

Europe PMC DOI

hedged sentences

0.3473

closest p · 6.9× alpha

0.3473

boldest claim

The sentences

a nonsignificant trendp = 0.3473not close (p > 0.1)

Losartan treatment significantly increased plasma concentrations of ANG II in NI and 5 days I3C-induced rats, with a nonsignificant trend toward an increase in 13 days I3C-induced rats ( p = 0.3473). 5 days I3C-induction led to about 4-fold higher kidney ANG II levels in comparison to NI rats, which were significantly reduced after 13 days I3C-induction, but to levels statistically higher than NI rats (164.6 ± 12.6 vs. 216.1 ± 9.6 vs. 57.2 ± 4.2 fmol/g).

also in 5,406 other papers

did not reach statistical significanceno p-value reported

Still, it did not reach statistical significance due to high variability.

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.