Impact of Chorionic Somatomammotropin In Vivo RNA Interference Phenotype on Uteroplacental Expression of the IGF Axis.

However, in the fetal placenta of CSH RNAi PI-FGR pregnancies, IGF1R mRNA increased by 92%, although this did not reach statistical significance ( Figure 2 ), which may have been an attempt to upregulate IGF1R in the face of significantly reduced IGF1 mRNA in the fetal placenta ( Figure 1 ).

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