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Haptoglobin Gene Expression and Anthracycline-Related Cardiomyopathy in Childhood Cancer Survivors: A COG-ALTE03N1 Report.

JACC CardioOncol · 2023 · PMC10308004 · PMID 37397079

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Genetic determinants of HP gene expression and risk for anthracycline-related cardiomyopathy The HP genotype (model A) and the 2 SNVs taken together (rs35283911 and rs2000999) (model B) demonstrated 3.2-fold and 1.8-fold higher odds of cardiomyopathy, respectively, but these associations did not reach statistical significance ( Table 4 ).

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