Targeting NAD metabolism regulates extracellular adenosine levels to improve the cytotoxicity of CD8+ effector T cells in the tumor microenvironment of gastric cancer.

There was a decreasing trend in TNFα high MFI, with no significant difference (Fig. 5 d).

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This was further verified by flow cytometry, and a significant trend of apoptosis was found in AGS cells after treatment with FK866 (8 nM and 16 nM) for 2–3 days (Fig. 3 b, c).

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