Data-driven neuropathological staging and subtyping of TDP-43 proteinopathies.

Individuals with a secondary diagnosis of ALS were more likely to be Subtype 2 (85.7% of seven individuals with secondary neuropathological evidence of ALS versus 52.9% of 119 individuals without secondary neuropathological evidence of ALS), but this trend did not reach statistical significance ( P = 0.1928).

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