ACSL1 is a key regulator of inflammatory and macrophage foaming induced by short-term palmitate exposure or acute high-fat feeding.

To further dissect the effect of PA short-term treatment on the expression of the ACSL family members, we assessed gene expression of ACSL1, ACSL3, ACSL4, ACSL5, and ACSL6 and found that PA short-term treatment significantly increased the expression of both ACSL1 and ACSL3 in macrophages, while the reduction in ACSL4 and ACSL5 mRNA expression did not reach statistical significance.

also in 111,027 other papers